IVF (In Vitro Fertilization) and Treatment

The technique of surgically taking a woman’s eggs and fertilising them with a man’s sperm in a controlled laboratory environment is known as IVF (In Vitro Fertilization). The IVF procedure is used when a fallopian tube restriction prevents normal ovum-sperm fertilisation.

IVF offers a great deal of hope to couples who have struggled to conceive naturally and who have seen no success after 12 consecutive cycles of artificial insemination. Modern facilities make IVF a prominent medical technology in India nowadays. In fact, according to recent trends, 32% of American and British patients travelling to India for medical treatment use IVF. For instance, Dr. Nandita Palshetkar, a leading expert in IVF medicine both in India and internationally, has clinics in various important Indian cities.

IVF – How Is It Performed?

There are six major steps involved:

• Daily injections are used to suppress the monthly cycle for roughly two weeks.
• Follicle stimulating hormone (FSH) injections given daily for 10 to 12 days to increase egg production.
• About 34–38 hours before to egg collection, there will be a progress check and final egg boost injection.
• Sedation is used to prepare the patient for egg collection, which is followed by ultrasound-guided needle extraction of eggs from each ovary. After this operation, some women could bleed a little bit vaginally.
• The eggs are fertilised with your partner’s sperm for 5–6 days in a supervised laboratory setting. Progesterone or hCG (chorionic gonadotrophin) is administered to you to get the womb ready for an embryo.
• Based on the counselling provided previously, the patient’s age, and overall health, an embryo transfer is carried out.

An egg must leave the ovary and combine with a sperm in order for pregnancy to happen. This union, which is known as fertilisation, typically takes place inside the fallopian tube, which connects the uterus (womb) to the ovary. However, in IVF, after the collection of the eggs and sperm, the union takes place in a lab. Embryos are subsequently moved to the uterus where they can continue to develop.

With the most cutting-edge reproductive technologies, Infertility India offers quality infertility treatments at reasonable prices. concentrate on IVF clinic, IVF therapy, IVF cycle, and IVF Due to surgery, tubal pregnancy, infection, or both, the fallopian tubes are nonexistent or obstructed (STD, or Tuberculosis) reduced sperm count or motility (IVF is typically done for levels greater than 5 million per ml). for counts per millilitre fewer than 5 million. ICSI is a superior choice.) patients for whom all other treatments, such as intra uterine insemination to induce ovulation, have failed.

Patients with unexplained infertility who, despite usual therapies, are unable to conceive despite all investigations on the pair being normal.

Patients who have tried all conventional treatments for infertility without success.

Patients seeking conception through the process of egg and embryo donation. Our unit’s IVF success rates, which range from 20 to 30%, are similar to those of the top centres worldwide.

There are five major steps in the IVF and embryo transfer sequence:

• Monitor the development of ripening egg(s) in the ovaries
• Collection of eggs
• Obtaining the sperm
• Putting the eggs and sperm together in the laboratory, and providing correct conditions for fertilization and early embryo growth
• Transferring the embryos into the uterus

Fertility medicines are provided in accordance with each individual case in order to regulate the period of egg ripening and increase the likelihood of collecting a significant number of eggs. We perform an ultrasound of the ovaries to evaluate the growth of the eggs and a blood/urine test to measure hormone levels before determining the egg retrieval timetable. Using a hollow needle and the ultrasound image as a guide, the trans-vaginal egg retrieval operation is carried out (this is completely comfortable under adequate sedation and local anesthesia). The needle is used to delicately retrieve eggs from the ovaries. “Follicular aspiration” is the term used for this. The egg will not develop properly if it is gathered too early, and if it is retrieved too late, the egg may have have been expelled from the ovary and lost.

Our embryologists quickly identify the eggs in our specialised IVF laboratory. To enable fertilisation, they are put in incubators alongside the sperm. The fertilised eggs—now known as embryos—are carefully inspected at regular intervals to make sure that fertilisation and cell division have occurred.

2 or 3 days following egg harvesting, embryos are often implanted in the wife’s uterus. For the purpose of exposing the womb’s neck, a speculum is placed into the vagina (cervix). The embryos are placed in a tiny drop of fluid before being carefully inserted into the uterus through a catheter, frequently with ultrasound guidance. After the transfer, there is a period of rest, followed by blood tests and perhaps an ultrasound to see if a pregnancy has developed.

To summarize, the IVF procedure consists of:

• Controlled ovarian stimulation using medications (such as gonadotrophins and analogues of GNRH) to increase egg production.
• Utilizing serial Estradiol hormone estimation and vaginal sonography, one can track the growth of follicles and eggs.
• HCG (Human Chorionic Gonadotrophins) injections are given when the two leading follicles are 18 mm in diameter.
• 35 to 37 hours after the HCG injection, oocyte or egg retrieval is performed under brief general anaesthesia.
• Laboratory isolation and identification of eggs.
• sperm collecting and laboratory processing.
• Fertilization of the egg with the sperm.
• 2 to 5 days after fertilisation, embryos begin to develop.
• After two days (four cell embryo), three days (six-eight cell embryo), or five days (blastocyst stage), good quality embryos are transferred back into the womb.